a disease caused by deficiency of niacin or tryptophan (or by a defect in the metabolic conversion of tryptophan to niacin); characterized by gastrointestinal disturbances and erythema and nervous or mental disorders; may be caused by malnutrition or alcoholism or other nutritional impairments
source: WordNet 3.0
An erythematous affection of the skin, with severe constitutional and nervous symptoms, endemic in Northern Italy.